Supraphysiological androgen levels induce cellular senescence in human prostate cancer cells through the Src-Akt pathway

BACKGROUND: Prostate cancer (PCa) is the second leading cause of cancer mortality of men in Western countries. The androgen receptor (AR) and AR-agonists (androgens) are required for the development and progression of the normal prostate as well as PCa. However, it is discussed that in addition to t...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Roediger, Julia, Hessenkemper, Wiebke, Bartsch, Sophie, Manvelyan, Marina, Huettner, Soeren S, Liehr, Thomas, Esmaeili, Mohsen, Foller, Susan, Petersen, Iver, Grimm, Marc-Oliver, Baniahmad, Aria
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171558/
https://ncbi.nlm.nih.gov/pubmed/25216853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-214
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires