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Chemotherapy Enhances Cross-Presentation of Nuclear Tumor Antigens

Cross-presentation of tumor antigen is essential for efficient priming of naïve CD8(+) T lymphocytes and induction of effective anti-tumor immunity. We hypothesized that the subcellular location of a tumor antigen could affect the efficiency of cross-presentation, and hence the outcome of anti-tumor...

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Detalhes bibliográficos
Main Authors: Anyaegbu, Chidozie C., Lake, Richard A., Heel, Kathy, Robinson, Bruce W., Fisher, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171494/
https://ncbi.nlm.nih.gov/pubmed/25243472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107894
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