Tumor cells, rather than dendritic cells, deliver antigen to the lymph node for cross-presentation

It is widely accepted that generation of tumor specific CD8+ T-cell responses occur via cross-priming; however the source of tumor antigen for this event is unknown. We examined the source and form of tumor antigen required for cross-presentation in the local lymph node (LN) using a syngeneic mouse...

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Dettagli Bibliografici
Autori principali: McDonnell, Alison M., Currie, Andrew J., Brown, Matthew, Kania, Kasia, Wylie, Ben, Cleaver, Amanda, Lake, Richard, Robinson, Bruce W.S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489739/
https://ncbi.nlm.nih.gov/pubmed/23162751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20493
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