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Tumor cells, rather than dendritic cells, deliver antigen to the lymph node for cross-presentation
It is widely accepted that generation of tumor specific CD8+ T-cell responses occur via cross-priming; however the source of tumor antigen for this event is unknown. We examined the source and form of tumor antigen required for cross-presentation in the local lymph node (LN) using a syngeneic mouse...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3489739/ https://ncbi.nlm.nih.gov/pubmed/23162751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20493 |
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