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Enhanced ER entry of tumor antigen is crucial for cross-presentation induced by dendritic cell-targeted vaccination
Efficient cross-presentation of protein antigens to cytotoxic T lymphocytes (CTLs) by dendritic cells (DCs) is essential for the success of prophylactic and therapeutic vaccines. Here, we report a previously underappreciated pathway involving antigen entry into the endoplasmic reticulum (ER) critica...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3858385/ https://ncbi.nlm.nih.gov/pubmed/24218449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302312 |
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