Targeting the immunoregulator SRA/CD204 potentiates specific dendritic cell vaccine-induced T cell response and antitumor immunity

Although dendritic cell (DC) vaccines offer promise as cancer immunotherapy, further improvements are needed to amplify their clinical therapeutic efficacy. The pattern recognition scavenger receptor SRA/CD204 attenuates the ability of DCs to activate CD8(+) T cell responses. Therefore, we examined...

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Main Authors: Yi, Huanfa, Guo, Chunqing, Yu, Xiaofei, Gao, Ping, Qian, Jie, Zuo, Daming, Manjili, Masoud H., Fisher, Paul B., Subjeck, John R., Wang, Xiang-Yang
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213980/
https://ncbi.nlm.nih.gov/pubmed/21914786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1801
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