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Family-Based Association Test Using Both Common and Rare Variants and Accounting for Directions of Effects for Sequencing Data
Current family-based association tests for sequencing data were mainly developed for identifying rare variants associated with a complex disease. As the disease can be influenced by the joint effects of common and rare variants, common variants with modest effects may not be identified by the method...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4171487/ https://ncbi.nlm.nih.gov/pubmed/25244564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107800 |
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