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Family-Based Association Test Using Both Common and Rare Variants and Accounting for Directions of Effects for Sequencing Data

Current family-based association tests for sequencing data were mainly developed for identifying rare variants associated with a complex disease. As the disease can be influenced by the joint effects of common and rare variants, common variants with modest effects may not be identified by the method...

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Hlavní autoři: Chung, Ren-Hua, Tsai, Wei-Yun, Martin, Eden R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171487/
https://ncbi.nlm.nih.gov/pubmed/25244564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107800
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