Vascular damage and anti-angiogenic effects of tumor vessel-targeted adenovirus-mediated herpes simplex virus thymidine kinase gene

AIM: To explore the therapeutic efficacy and mechanism of herpes simplex virus-thymidine kinase (HSV-tk) targeting angiogenesis against hepatocellular carcinoma in vivio and in vitro. METHODS: Recombinant adenovirus containing kinase domain insert with receptor (KDR) or cytomegalovirus (CMV) promote...

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Detalhes bibliográficos
Main Authors: Li, Bao-Jin, Zhang, Chao, Yi, Yuan-Xue, Hao, Ying, Liu, Xiao-Ping, Ou, Qing-Jia
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2007
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171177/
https://ncbi.nlm.nih.gov/pubmed/17663519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i29.4006
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