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Treatment of experimental human mesothelioma using adenovirus transfer of the herpes simplex thymidine kinase gene.

OBJECTIVE: The authors demonstrate the ability of an adenovirus vector expressing the herpes simplex thymidine kinase (HSVtk) gene to treat human malignant mesothelioma growing within the peritoneal cavity of severe combined immunodeficient (SCID) mice. BACKGROUND DATA: Introduction of the HSVtk gen...

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Autores principales: Smythe, W R, Hwang, H C, Elshami, A A, Amin, K M, Eck, S L, Davidson, B L, Wilson, J M, Kaiser, L R, Albelda, S M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234759/
https://ncbi.nlm.nih.gov/pubmed/7618973
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