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Hypophosphatasia - pathophysiology and treatment

Hypophosphatasia (HPP) is the inborn-error-of-metabolism caused by loss-of-function mutation(s) in the gene that encodes the tissue-nonspecific isozyme of alkaline phosphatase (TNAP). The disease has been classified according to patient age when the first signs and symptoms manifest; i.e., perinatal...

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Detalhes bibliográficos
Main Authors: Millán, José Luis, Plotkin, Horacio
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171060/
https://ncbi.nlm.nih.gov/pubmed/25254037
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