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Pathophysiology of hypophosphatasia and the potential role of asfotase alfa

Hypophosphatasia (HPP) is an inherited systemic bone disease that is characterized by bone hypomineralization. HPP is classified into six forms according to the age of onset and severity as perinatal (lethal), perinatal benign, infantile, childhood, adult, and odontohypophosphatasia. The causative g...

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Detalhes bibliográficos
Publicado no:Ther Clin Risk Manag
Autor principal: Orimo, Hideo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876073/
https://ncbi.nlm.nih.gov/pubmed/27274262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S87956
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