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TLR-Mediated Inflammatory Responses to Streptococcus pneumoniae Are Highly Dependent on Surface Expression of Bacterial Lipoproteins

Streptococcus pneumoniae infections induce inflammatory responses that contribute toward both disease pathogenesis and immunity, but the host–pathogen interactions that mediate these effects are poorly defined. We used the surface lipoprotein-deficient ∆lgt pneumococcal mutant strain to test the hyp...

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Main Authors: Tomlinson, Gillian, Chimalapati, Suneeta, Pollard, Tracey, Lapp, Thabo, Cohen, Jonathan, Camberlein, Emilie, Stafford, Sian, Periselneris, Jimstan, Aldridge, Christine, Vollmer, Waldemar, Picard, Capucine, Casanova, Jean-Laurent, Noursadeghi, Mahdad, Brown, Jeremy
Format: Artigo
Jezik:Inglês
Izdano: AAI 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170674/
https://ncbi.nlm.nih.gov/pubmed/25172490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401413
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