TLR-Mediated Inflammatory Responses to Streptococcus pneumoniae Are Highly Dependent on Surface Expression of Bacterial Lipoproteins

Streptococcus pneumoniae infections induce inflammatory responses that contribute toward both disease pathogenesis and immunity, but the host–pathogen interactions that mediate these effects are poorly defined. We used the surface lipoprotein-deficient ∆lgt pneumococcal mutant strain to test the hyp...

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Detalhes bibliográficos
Main Authors: Tomlinson, Gillian, Chimalapati, Suneeta, Pollard, Tracey, Lapp, Thabo, Cohen, Jonathan, Camberlein, Emilie, Stafford, Sian, Periselneris, Jimstan, Aldridge, Christine, Vollmer, Waldemar, Picard, Capucine, Casanova, Jean-Laurent, Noursadeghi, Mahdad, Brown, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2014
Assuntos:
Innate Immunity and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170674/
https://ncbi.nlm.nih.gov/pubmed/25172490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401413
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