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DC Priming by M. vaccae Inhibits Th2 Responses in Contrast to Specific TLR2 Priming and Is Associated with Selective Activation of the CREB Pathway

The environmental mycobacterium, M. vaccae has been used in mouse models to support the contemporary hygiene hypothesis that non-pathogenic microorganisms reduce allergy associated T helper (Th)2 responses and inflammatory diseases by augmenting regulatory T cells. However, data for human models and...

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Detalles Bibliográficos
Main Authors: Le Bert, Nina, Chain, Benjamin M., Rook, Graham, Noursadeghi, Mahdad
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069967/
https://ncbi.nlm.nih.gov/pubmed/21483768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018346
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