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Oncogene-mediated regulation of p53 ISGylation and functions

Oncogene-mediated cellular transformation is a multistep process involving activation of growth-promoting pathways as well as inactivation of tumor suppressors. We recently found that ISGylation of the p53 tumor suppressor is an important novel mechanism to control its stability. Here we identified...

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Detalhes bibliográficos
Main Authors: Huang, Yi-Fu, Bulavin, Dmitry V.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170631/
https://ncbi.nlm.nih.gov/pubmed/25071020
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