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Angiogenin functionally interacts with p53 and regulates p53 mediated apoptosis and cell survival
Angiogenin, a 14-kDa multi-functional pro-angiogenic growth factor, is up-regulated in several types of cancers. Anti-angiogenin monoclonal antibodies used as antagonists inhibited the establishment, progression, and metastasis of human cancer cells in athymic mice (Olson et al. 1994). Silencing ang...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337890/ https://ncbi.nlm.nih.gov/pubmed/22266868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.648 |
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