Upregulation of microRNA135a-3p and death receptor 5 plays a critical role in Tanshinone I sensitized prostate cancer cells to TRAIL induced apoptosis

Though tumor necrosis factor related apoptosis inducing ligand (TRAIL) has been used as a potent anticancer agent, TRAIL resistance is a hot-issue in cancer therapy. We investigated the antitumor mechanism of Tanshinone I to sensitize prostate cancer cells to TRAIL. Comibination of Tanshinone I and...

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Detalhes bibliográficos
Main Authors: Shin, Eun Ah, Sohn, Eun Jung, Won, Gunho, Choi, Jeong-Un, Jeong, Myongsuk, Kim, Bonglee, Kim, Min-Jeong, Kim, Sung-Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170628/
https://ncbi.nlm.nih.gov/pubmed/25015549
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