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Decursin enhances TRAIL‐induced apoptosis through oxidative stress mediated‐ endoplasmic reticulum stress signalling in non‐small cell lung cancers

BACKGROUND AND PURPOSE: The TNF‐related apoptosis‐inducing ligand (TRAIL) is a promising anticancer agent due to its remarkable ability to selectively kill tumour cells. However, because most tumours exhibit resistance to TRAIL‐induced apoptosis, the development of combination therapies to overcome...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Kim, Jaekwang, Yun, Miyong, Kim, Eun‐Ok, Jung, Deok‐Beom, Won, Gunho, Kim, Bonglee, Jung, Ji Hoon, Kim, Sung‐Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341238/
https://ncbi.nlm.nih.gov/pubmed/26661339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13408
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