Upregulation of death receptor 5 and activation of caspase 8/3 play a critical role in ergosterol peroxide induced apoptosis in DU 145 prostate cancer cells

BACKGROUND: Though ergosterol peroxide (EP) derived from Neungyi mushrooms (Sarcodon aspratus) was known to have cytotoxic, apoptotic, anti-inflammatory and antimycobacterial effects, the underlying molecular mechanism of EP still remains unclear. Thus, in the present study, the apoptotic mechanism...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Han, Jonghyun, Sohn, Eun Jung, Kim, Bonglee, Kim, Sunhee, Won, Gunho, Yoon, Sangwook, Lee, Jihyun, Kim, Moon Joon, Lee, Hojin, Chung, Kyujin, Kim, Sung-hoon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265345/
https://ncbi.nlm.nih.gov/pubmed/25506265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-014-0117-5
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