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Short-term exposure to a neuroactive steroid increases α(4) GABA(A) receptor subunit levels in association with increased anxiety in the female rat

Previous work from this laboratory has demonstrated that withdrawal from the neuroactive steroid 3α,5α-THP (3α-hydroxy-5α-pregnan-20-one) after 3-week exposure to its parent compound, progesterone (P), increases anxiety and produces benzodiazepine (BDZ) insensitivity in female rats. These events wer...

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Autors principals: Gulinello, M., Gong, Q.H., Li, X., Smith, S.S.
Format: Artigo
Idioma:Inglês
Publicat: 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170586/
https://ncbi.nlm.nih.gov/pubmed/11489254
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