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Progesterone withdrawal increases the anxiolytic actions of gaboxadol: role of α4βδ GABA(A) receptors
Hippocampal α4βδ GABA(A) receptors (GABA(A)-R) are increased following progesterone withdrawal (PWD) in a rodent model of premenstrual anxiety. This α4βδ receptor isoform uniquely responds to the GABA agonist gaboxadol (THIP) with a maximum current greater than that gated by GABA, and is potentiated...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167748/ https://ncbi.nlm.nih.gov/pubmed/12544828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.wnr.0000050303.92401.9e |
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