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Ethanol effects on GABA-gated current in a model of increased α4βδ GABA(A) receptor expression depend on time course and preexposure to low concentrations of the drug

Several recent studies have suggested that αβδ subtypes of γ-aminobutyric acid type A (GABA(A)) receptors (δ-GABAR) are a target for low dose ethanol (< 30 mM). However, there are also conflicting reports suggesting that only high doses of the drug (100 mM) modulate these receptors. In addition,...

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Détails bibliographiques
Auteurs principaux: Smith, Sheryl S., Gong, Qi Hua
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658629/
https://ncbi.nlm.nih.gov/pubmed/17591545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2007.04.007
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