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GATA-3 dose-dependent checkpoints in early T cell commitment()
GATA-3 expression is crucial for T cell development and peaks during commitment to the T-cell lineage, midway through the CD4(−)CD8(−) (DN) 1-3 stages. We used RNA interference and conditional deletion to reduce GATA-3 protein acutely at specific points during T-cell differentiation in vitro. Even m...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4170028/ https://ncbi.nlm.nih.gov/pubmed/25172496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301663 |
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