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Transcriptional establishment of cell-type identity: dynamics and causal mechanisms of T-cell lineage commitment
Precursor cell entry into the T-cell developmental pathway can be divided into two phases by the closure of T-lineage commitment. As cells decide against the last alternative options to the T-cell fate, they turn on the transcription factor Bcl11b and silence expression of a group of multipotent pro...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3990665/ https://ncbi.nlm.nih.gov/pubmed/24135716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2013.78.020271 |
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