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An Early T Cell Lineage Commitment Checkpoint Dependent on the Transcription Factor Bcl11b

The identities of the regulators that mediate commitment of hematopoietic precursors to the T lymphocyte lineage have been unknown. The last stage of T lineage commitment in vivo involves mechanisms to suppress natural killer cell potential, to suppress myeloid and dendritic cell potential, and to s...

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Hlavní autoři: Li, Long, Leid, Mark, Rothenberg, Ellen V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935300/
https://ncbi.nlm.nih.gov/pubmed/20595614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1188989
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