Cell type–specific actions of Bcl11b in early T-lineage and group 2 innate lymphoid cells

The zinc finger transcription factor, Bcl11b, is expressed in T cells and group 2 innate lymphoid cells (ILC2s) among hematopoietic cells. In early T-lineage cells, Bcl11b directly binds and represses the gene encoding the E protein antagonist, Id2, preventing pro-T cells from adopting innate-like f...

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發表在:J Exp Med
Main Authors: Hosokawa, Hiroyuki, Romero-Wolf, Maile, Yang, Qi, Motomura, Yasutaka, Levanon, Ditsa, Groner, Yoram, Moro, Kazuyo, Tanaka, Tomoaki, Rothenberg, Ellen V.
格式: Artigo
語言:Inglês
出版: Rockefeller University Press 2019
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037248/
https://ncbi.nlm.nih.gov/pubmed/31653691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190972
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