Genetic variants of ApoE and ApoER2 differentially modulate endothelial function

It is poorly understood why there is greater cardiovascular disease risk associated with the apolipoprotein E4 (apoE) allele vs. apoE3, and also greater risk with the LRP8/apolipoprotein E receptor 2 (ApoER2) variant ApoER2-R952Q. Little is known about the function of the apoE–ApoER2 tandem outside...

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Detalhes bibliográficos
Main Authors: Ulrich, Victoria, Konaniah, Eddy S., Herz, Joachim, Gerard, Robert D., Jung, Eunjeong, Yuhanna, Ivan S., Ahmed, Mohamed, Hui, David Y., Mineo, Chieko, Shaul, Philip W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169937/
https://ncbi.nlm.nih.gov/pubmed/25197062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402106111
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