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Loss of Reelin protects against atherosclerosis by reducing leukocyte-endothelial adhesion and lesion macrophage accumulation

The multimodular glycoprotein Reelin controls neuronal migration and synaptic transmission by binding to Apolipoprotein E receptor-2 (Apoer2) and very low-density lipoprotein receptor (Vldlr) on neurons. In the periphery, Reelin is produced by the liver, circulates in blood and promotes thrombosis a...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Ding, Yinyuan, Huang, Linzhang, Xian, Xunde, Yuhanna, Ivan S., Wasser, Catherine R., Frotscher, Michael, Mineo, Chieko, Shaul, Philip W., Herz, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053773/
https://ncbi.nlm.nih.gov/pubmed/26980442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aad5578
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