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Single cell sequencing reveals low levels of aneuploidy across mammalian tissues

Whole-chromosome copy number alterations, also known as aneuploidy, are associated with adverse consequences in most cells and organisms. However, high frequencies of aneuploidy have been reported to occur naturally in the mammalian liver and brain, fueling speculation that aneuploidy provides a sel...

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Main Authors: Knouse, Kristin A., Wu, Jie, Whittaker, Charles A., Amon, Angelika
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169915/
https://ncbi.nlm.nih.gov/pubmed/25197050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415287111
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