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Chromosome segregation fidelity in epithelia requires tissue architecture

Much of our understanding of chromosome segregation is based on cell culture systems. Here, we examine the importance of the tissue environment for chromosome segregation by comparing chromosome segregation fidelity across several primary cell types in native and nonnative contexts. We discover that...

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Bibliographische Detailangaben
Veröffentlicht in:Cell
Hauptverfasser: Knouse, Kristin A., Lopez, Kristina E., Bachofner, Marc, Amon, Angelika
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151153/
https://ncbi.nlm.nih.gov/pubmed/30146160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.07.042
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