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Translocalized IgA mediates neutralization and stimulates innate immunity inside infected cells
IgA is the most prevalent antibody type on mucosal surfaces and the second most prevalent antibody in circulation, yet its role in immune defense is not fully understood. Here we show that IgA is carried inside cells during virus infection, where it activates intracellular virus neutralization and i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169910/ https://ncbi.nlm.nih.gov/pubmed/25169018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410980111 |
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