Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET

Dysregulation of the von Hippel–Lindau/hypoxia-inducible transcription factor (HIF) signaling pathway promotes clear cell renal cell carcinoma (ccRCC) progression and metastasis. The protein kinase GAS6/AXL signaling pathway has recently been implicated as an essential mediator of metastasis and rec...

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Detalhes bibliográficos
Main Authors: Rankin, Erinn B., Fuh, Katherine C., Castellini, Laura, Viswanathan, Kartik, Finger, Elizabeth C., Diep, Anh N., LaGory, Edward L., Kariolis, Mihalis S., Chan, Andy, Lindgren, David, Axelson, Håkan, Miao, Yu R., Krieg, Adam J., Giaccia, Amato J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169907/
https://ncbi.nlm.nih.gov/pubmed/25187556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404848111
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