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IRAK4 Dimerization and Trans-autophosphorylation are Induced by Myddosome Assembly
Trans -autophosphorylation is among the most prevalent means of protein kinase activation, yet its molecular basis is poorly defined. In Toll-like receptor and interleukin-1 receptor signaling pathways, the kinase IRAK4 is recruited to the membrane proximal adapter MyD88 through death domain (DD) in...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169746/ https://ncbi.nlm.nih.gov/pubmed/25201411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.08.006 |
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