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Helical assembly in the death domain (DD) superfamily

Death domain (DD) superfamily members play a central role in apoptotic and inflammatory signaling through formation of oligomeric molecular scaffolds. These scaffolds promote the activation of proinflammatory and apoptotic initiator caspases, as well as Ser/Thr kinases. Interactions between DDs are...

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Detalhes bibliográficos
Main Authors: Ferrao, Ryan, Wu, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320699/
https://ncbi.nlm.nih.gov/pubmed/22429337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2012.02.006
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