Pituitary Adenylate Cyclase-Activating Polypeptide Ameliorates Experimental Acute Ileitis and Extra-Intestinal Sequelae

BACKGROUND: The neuropeptide Pituitary adenylate cyclase-activating polypeptide (PACAP) plays pivotal roles in immunity and inflammation. So far, potential immune-modulatory properties of PACAP have not been investigated in experimental ileitis. METHODOLOGY/PRINCIPAL FINDINGS: Mice were perorally in...

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Main Authors: Heimesaat, Markus M., Dunay, Ildiko R., Schulze, Silvia, Fischer, André, Grundmann, Ursula, Alutis, Marie, Kühl, Anja A., Tamas, Andrea, Toth, Gabor, Dunay, Miklos P., Göbel, Ulf B., Reglodi, Dora, Bereswill, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169633/
https://ncbi.nlm.nih.gov/pubmed/25238233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108389
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