Pituitary Adenylate Cyclase-Activating Polypeptide—A Neuropeptide as Novel Treatment Option for Subacute Ileitis in Mice Harboring a Human Gut Microbiota

The neuropeptide Pituitary adenylate cyclase-activating polypeptide (PACAP) is well-known for its important functions in immunity and inflammation. Data regarding anti-inflammatory properties of PACAP in the intestinal tract are limited, however. In our present preclinical intervention study we addr...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Bereswill, Stefan, Escher, Ulrike, Grunau, Anne, Kühl, Anja A., Dunay, Ildiko R., Tamas, Andrea, Reglodi, Dora, Heimesaat, Markus M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438926/
https://ncbi.nlm.nih.gov/pubmed/30967875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00554
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