Pituitary Adenylate Cyclase-Activating Polypeptide Ameliorates Experimental Acute Ileitis and Extra-Intestinal Sequelae

BACKGROUND: The neuropeptide Pituitary adenylate cyclase-activating polypeptide (PACAP) plays pivotal roles in immunity and inflammation. So far, potential immune-modulatory properties of PACAP have not been investigated in experimental ileitis. METHODOLOGY/PRINCIPAL FINDINGS: Mice were perorally in...

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Bibliografski detalji
Glavni autori: Heimesaat, Markus M., Dunay, Ildiko R., Schulze, Silvia, Fischer, André, Grundmann, Ursula, Alutis, Marie, Kühl, Anja A., Tamas, Andrea, Toth, Gabor, Dunay, Miklos P., Göbel, Ulf B., Reglodi, Dora, Bereswill, Stefan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169633/
https://ncbi.nlm.nih.gov/pubmed/25238233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108389
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