The impact of Toll-like-receptor-9 on intestinal microbiota composition and extra-intestinal sequelae in experimental Toxoplasma gondii induced ileitis

BACKGROUND: Following peroral Toxoplasma (T.) gondii infection, susceptible mice develop acute ileitis due to a microbiota-dependent Th1 type immunopathology. Toll-like-receptor (TLR)-9 is known to recognize bacterial DNA and mediates intestinal inflammation, but its impact on intestinal microbiota...

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Main Authors: Bereswill, Stefan, Kühl, Anja A, Alutis, Marie, Fischer, André, Möhle, Luisa, Struck, Daniela, Liesenfeld, Oliver, Göbel, Ulf B, Dunay, Ildikò R, Heimesaat, Markus M
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057803/
https://ncbi.nlm.nih.gov/pubmed/24932221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-4749-6-19
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