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Nucleotide-Oligomerization-Domain-2 Affects Commensal Gut Microbiota Composition and Intracerebral Immunopathology in Acute Toxoplasma gondii Induced Murine Ileitis

BACKGROUND: Within one week following peroral high dose infection with Toxoplasma (T.) gondii, susceptible mice develop non-selflimiting acute ileitis due to an underlying Th1-type immunopathology. The role of the innate immune receptor nucleotide-oligomerization-domain-2 (NOD2) in mediating potenti...

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Detalhes bibliográficos
Main Authors: Heimesaat, Markus M., Dunay, Ildiko R., Alutis, Marie, Fischer, André, Möhle, Luisa, Göbel, Ulf B., Kühl, Anja A., Bereswill, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139296/
https://ncbi.nlm.nih.gov/pubmed/25141224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105120
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