Thymidylate Synthase Genotype-Directed Chemotherapy for Patients with Gastric and Gastroesophageal Junction Cancers

BACKGROUND: Retrospective studies indicate associations between TSER (thymidylate synthase enhancer region) genotypes and clinical outcomes in patients receiving 5-FU based chemotherapy, but well-controlled prospective validation has been lacking. METHODS: In this phase II study (NCT00515216 registe...

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Detalhes bibliográficos
Principais autores: Goff, Laura W., Thakkar, Nilay, Du, Liping, Chan, Emily, Tan, Benjamin R., Cardin, Dana B., McLeod, Howard L., Berlin, Jordan D., Zehnbauer, Barbara, Fournier, Chloe, Picus, Joel, Wang-Gillam, Andrea, Lee, Wooin, Lockhart, A. Craig
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169411/
https://ncbi.nlm.nih.gov/pubmed/25232828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107424
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