Aberrant Production of Tenascin-C In Globoid Cell Leukodystrophy Alters Psychosine-Induced Microglial Functions

Globoid cell leukodystrophy (GLD), or Krabbe disease, is a rare and often fatal demyelinating disease caused by mutations in the galactocerebrosidase (galc) gene that result in accumulation of galactosylsphingosine (‘psychosine’). We recently reported that the extracellular matrix (ECM) protease, ma...

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Main Authors: Claycomb, Kumiko I., Winokur, Paige N., Johnson, Kasey M., Nicaise, Alexandra M., Giampetruzzi, Anthony W., Sacino, Anthony V., Snyder, Evan Y., Barbarese, Elisa, Bongarzone, Ernesto R., Crocker, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169335/
https://ncbi.nlm.nih.gov/pubmed/25192051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0000000000000117
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