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An In Vitro Model for the Study of Cellular Pathophysiology in Globoid Cell Leukodystrophy

The precise function of multi-nucleated microglia, called globoid cells, that are uniquely abundant in the central nervous system of globoid cell leukodystrophy (GLD) is unclear. This gap in knowledge has been hindered by the lack of an appropriate in vitro model for study. Herein, we describe a pri...

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Publicat a:J Vis Exp
Autors principals: Claycomb, Kumiko I., Johnson, Kasey M., Bongarzone, Ernesto R., Crocker, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353315/
https://ncbi.nlm.nih.gov/pubmed/25350151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51903
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