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An In Vitro Model for the Study of Cellular Pathophysiology in Globoid Cell Leukodystrophy

The precise function of multi-nucleated microglia, called globoid cells, that are uniquely abundant in the central nervous system of globoid cell leukodystrophy (GLD) is unclear. This gap in knowledge has been hindered by the lack of an appropriate in vitro model for study. Herein, we describe a pri...

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Bibliografske podrobnosti
izdano v:J Vis Exp
Main Authors: Claycomb, Kumiko I., Johnson, Kasey M., Bongarzone, Ernesto R., Crocker, Stephen J.
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353315/
https://ncbi.nlm.nih.gov/pubmed/25350151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51903
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