Structure reveals function of the dual variable domain immunoglobulin (DVD-Ig™) molecule

Several bispecific antibody-based formats have been developed over the past 25 years in an effort to produce a new generation of immunotherapeutics that target two or more disease mechanisms simultaneously. One such format, the dual-variable domain immunoglobulin (DVD-Ig™), combines the target bindi...

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Detalhes bibliográficos
Main Authors: Jakob, Clarissa G., Edalji, Rohinton, Judge, Russell A., DiGiammarino, Enrico, Li, Yingchun, Gu, Jijie, Ghayur, Tariq
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169029/
https://ncbi.nlm.nih.gov/pubmed/23549062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.23977
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