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Population pharmacokinetics of levodopa in subjects with advanced Parkinson's disease: levodopa-carbidopa intestinal gel infusion vs. oral tablets

AIMS: Levodopa-carbidopa intestinal gel (LCIG) provides continuous levodopa-carbidopa delivery through intrajejunal infusion. This study characterized the population pharmacokinetics of levodopa following a 16 h jejunal infusion of LCIG or frequent oral administration of levodopa-carbidopa tablets (...

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Autors principals: Othman, Ahmed A, Dutta, Sandeep
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168384/
https://ncbi.nlm.nih.gov/pubmed/24433449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12324
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