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Population pharmacokinetics of levodopa/carbidopa microtablets in healthy subjects and Parkinson’s disease patients

OBJECTIVES: Low dose, dispersible, levodopa/carbidopa microtablets with an automatic dose dispenser have been developed to facilitate individualized levodopa treatment. The aim of this study was to characterize the pharmacokinetics (PK) of levodopa and carbidopa after microtablet administration, and...

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Detalhes bibliográficos
Publicado no:Eur J Clin Pharmacol
Main Authors: Senek, Marina, Nyholm, Dag, Nielsen, Elisabet I.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132549/
https://ncbi.nlm.nih.gov/pubmed/29882153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-018-2497-2
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