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Pharmacokinetics of Levodopa, Carbidopa, and 3-O-Methyldopa Following 16-hour Jejunal Infusion of Levodopa-Carbidopa Intestinal Gel in Advanced Parkinson’s Disease Patients

Motor complications of Parkinson’s disease (PD) are a consequence of pulsatile dopaminergic stimulation from standard oral levodopa therapy. Levodopa–carbidopa intestinal gel (LCIG) is infused continuously via an intrajejunal percutaneous gastrostomy tube. This was the first study designed to charac...

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Bibliografische gegevens
Hoofdauteurs: Nyholm, Dag, Odin, Per, Johansson, Anders, Chatamra, Krai, Locke, Charles, Dutta, Sandeep, Othman, Ahmed A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675750/
https://ncbi.nlm.nih.gov/pubmed/23229334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9439-1
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