Jejunal Infusion of Levodopa–Carbidopa Intestinal Gel Versus Oral Administration of Levodopa–Carbidopa Tablets in Japanese Subjects with Advanced Parkinson’s Disease: Pharmacokinetics and Pilot Efficacy and Safety

BACKGROUND AND OBJECTIVE: Oral levodopa-carbidopa (LC-oral) treatment in advanced Parkinson’s disease (PD) is associated with motor complications due to large fluctuations in levodopa plasma concentrations. Levodopa–carbidopa intestinal gel (LCIG) provides individualized continuous levodopa–carbidop...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Pharmacokinet
Hauptverfasser: Othman, Ahmed A., Chatamra, Krai, Mohamed, Mohamed-Eslam F., Dutta, Sandeep, Benesh, Janet, Yanagawa, Masayoshi, Nagai, Masahiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2015
Schlagworte:
Original Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559582/
https://ncbi.nlm.nih.gov/pubmed/25875940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-015-0265-3
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