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Minocycline Enhances the Effectiveness of Nociceptin/Orphanin FQ during Neuropathic Pain

Nociceptin/orphanin FQ (N/OFQ) antinociception, which is mediated selectively by the N/OFQ peptide receptor (NOP), was demonstrated in pain models. In this study, we determine the role of activated microglia on the analgesic effects of N/OFQ in a rat model of neuropathic pain induced by chronic cons...

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Autors principals: Popiolek-Barczyk, Katarzyna, Rojewska, Ewelina, Jurga, Agnieszka M., Makuch, Wioletta, Zador, Ferenz, Borsodi, Anna, Piotrowska, Anna, Przewlocka, Barbara, Mika, Joanna
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168034/
https://ncbi.nlm.nih.gov/pubmed/25276817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/762930
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